Betamethasone (Betnovate-S) dipropionate, are effective in the treatment of corticosteroid-responsive dermatoses primarily because of their anti-inflammatory, antipruritic and vasoconstrictive actions. While the physiologic, pharmacologic, and clinical effects of the corticosteroids are well known, the exact mechanisms of their actions in each disease are uncertain. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes, by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A.
Prescription: Yes
Warnings: Do not use Betnovate S Ointment 20 gm in more than prescribed doses, on large areas of the body or for a prolonged time as it may change the levels of some hormones in the body. If you are known to be allergic to Betnovate S Ointment 20 gm or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Betnovate S Ointment 20 gm. Do not wrap or cover the treated area with plasters or bandages. Avoid using Betnovate S Ointment 20 gm for more than 5 days in children and on the face. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Betnovate S Ointment 20 gm catches fire and burns easily. If you have rosacea (redness and often red, small, pus-filled bumps on the face), psoriasis, acne, dermatitis (redness and swelling of the skin) around the mouth, chickenpox, cold sores, nappy rash, genital itching or other skin problems, glaucoma, cataracts, diabetes, adrenal gland, liver or blood circulation problems, inform your doctor before taking Betnovate S Ointment 20 gm. This medicine should not be used in bacterial/fungal infections, or napkin eruptions, without suitable concomitant anti-infective therapy. In rare cases, adrenal hormone suppression may also occur with Betnovate S Ointment 20 gm, especially in infants and children.
Medicine Interaction: Betnovate S Ointment 20 gm may interact with vitamin A-related drugs known as retinoids (isotretinoin, tretinoin, trifarotene, tazarotene, adapalene), and anti-cancer drugs (alitretinoin, bexarotene).
Drug Schedule: Schedule H Prescription Drug
Side Effects: The most common side effects following nasal inhalation of triamcinolone acetonide are nasal irritation and itching, increased cough, Nausea or vomiting, sore throat, nasal congestion, sneezing, nasal burning, bloody nasal discharge, and nasal dryness. Other adverse effects reported with intranasal triamcinolone acetonide include headache, dizziness, and watery eyes. All of these are either mild or uncommon.problems with your vision,
swelling, rapid weight gain, feeling short of breath,
severe depression, unusual thoughts or behavior, seizure (convulsions),
bloody or tarry stools, coughing up blood,
pancreatitis (severe pain in your upper stomach spreading to your back, Nausea and vomiting, fast heart rate),
low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling) or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).
Less serious side effects may include:
sleep problems (insomnia), mood changes,
acne, dry skin, thinning skin, bruising or discoloration,
slow wound healing,
increased sweating,
headache, dizziness, spinning sensation,
Nausea, stomach pain, bloating,
muscle weakness,
changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist)
How to Store it: Store protected from light at a temperature not exceeding 25 C. Do not freeze.
Over Dose: Store protected from light at a temperature not exceeding 25 C. Do not freeze.
Precautions: Store protected from light at a temperature not exceeding 25 C. Do not freeze.
Missed Dose: Store protected from light at a temperature not exceeding 25 C. Do not freeze.
