The precise mechanism by which Brivasure exerts its anticonvulsant Activity is not known. Brivasure displays a high and selective affinity for synaptic vesicle protein 2A (SV2A) in the brain, which may contribute to the anticonvulsant effect.
Brivasure binds SV2A with high affinity. SV2A is known to play a role in epileptogenesis through modulation of synaptic GABA release. It is thought that brivaracetam exerts its anti-epileptogenic effects through its binding to SV2A. Brivasure is also known to inhibit Na+ channels which may also contribute to its anti-epileptogenic action
Prescription: Yes
Warnings: Do not take Brivasure-75 Tablet 10's if you are known to be allergic to Brivasure-75 Tablet 10's. Inform your doctor if you have suicidal ideation or behaviour symptoms, drug addiction, chronic lung diseases, muscle weakness, heart problems, liver/kidney impairment. Do not stop taking Brivasure-75 Tablet 10's without consulting your doctor to avoid precipitating seizures. Avoid intake of Brivasure-75 Tablet 10's if you are pregnant or planning for pregnancy or nursing mothers unless prescribed by the doctor. Brivasure-75 Tablet 10's should not be given to children unless prescribed. Brivasure-75 Tablet 10's causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Brivasure-75 Tablet 10's as it could lead to increased dizziness and sleepiness. Taking Brivasure-75 Tablet 10's with opioids analgesics or pain killers like oxycodone can cause respiratory failure, coma, and even leading to death, so avoid its intake together. If you are taking any sleeping pills or tranquillizers, let your doctor know about this as Brivasure-75 Tablet 10's interacts with these drugs to cause sleepiness, drowsiness, and dizziness and affect your daily Activity. Brivasure-75 Tablet 10's contain lactose (a type of sugar), If you have an intolerance to some sugars, contact your doctor before taking Brivasure-75 Tablet 10's. Brivasure-75 Tablet 10's may be habit-forming. Misuse can cause addiction, overdose, or death.
Medicine Interaction: Brivasure-75 Tablet 10's may interact with other anticonvulsants (carbamazepine, phenytoin, levetiracetam, gabapentin, lamotrigine, pregabalin, topiramate), anti-anxiety (alprazolam, estazolam, midazolam, lorazepam, diazepam, clonazepam)antibiotics (rifampicin), painkiller (propoxyphene, buprenorphine, morphine, fentanyl, oxycodone, tramadol, codeine), antipsychotic (lithium), anti-coagulant (warfarin), antihistamine (diphenhydramine, cetirizine), a medicine used to treat symptoms of narcolepsy (sodium oxybate).
Side Effects: Most common adverse reactions (at least 5% for Brivasure and at least 2% more frequently than placebo) are somnolence/sedation, dizziness, fatigue, and Nausea or vomiting.
How to Store it: Store at a temperature not exceeding 30 C, protected from light and moisture.
Over Dose: Store at a temperature not exceeding 30 C, protected from light and moisture.
Precautions: Store at a temperature not exceeding 30 C, protected from light and moisture.
Missed Dose: Store at a temperature not exceeding 30 C, protected from light and moisture.
