Sitagliptin 50 mg and Metformin 500 mg Tablets

Uses of Sitagliptin 50 mg and Metformin 500 mg Tablets

This medication is primarily used to improve glycemic control in adults with type 2 diabetes mellitus. It is often prescribed when diet and exercise alone do not provide adequate control over blood sugar levels. The combination of Sitagliptin and Metformin works by enhancing insulin secretion in response to meals and decreasing glucose production by the liver.

Benefits of Sitagliptin 50 mg and Metformin 500 mg Tablets

The dual mechanism of action provided by Sitagliptin and Metformin offers several benefits:

• Improved control of blood glucose levels
• Potential weight neutrality or modest weight loss
• Low risk of hypoglycemia when used without insulin or sulfonylureas
• Reduction in blood sugar spikes after meals

Side Effects of Sitagliptin 50 mg and Metformin 500 mg Tablets

While this medication can be beneficial, it may also cause side effects. Common side effects include:

• Nausea and diarrhea
• Abdominal pain
• Headache
• Nasopharyngitis (common cold)

Rare but serious side effects may include lactic acidosis, a buildup of lactic acid in the blood, and pancreatitis. If you experience severe side effects, contact your healthcare provider immediately.

How to Use Sitagliptin 50 mg and Metformin 500 mg Tablets

Take this medication as prescribed by your healthcare provider, usually once or twice daily with meals to reduce gastrointestinal side effects. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Do not adjust your dose without consulting your healthcare provider.

How Sitagliptin 50 mg and Metformin 500 mg Tablets Works

Sitagliptin works by inhibiting the DPP-4 enzyme, which results in increased levels of incretin hormones. These hormones help increase insulin release in response to high blood sugar levels and decrease the amount of sugar produced by the liver. Metformin reduces glucose production by the liver and improves insulin sensitivity, making body cells use insulin more effectively.

Storage

Store the tablets at room temperature, away from light and moisture. Do not store in the bathroom. Keep all medications out of the reach of children and pets.

Caution and Warning

• Not recommended for patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.
• Carefully monitor renal function before initiation and periodically thereafter.
• Inform your healthcare provider about all your medical conditions and medications to avoid potential interactions.
• Not suitable for individuals with severe renal impairment, acute or chronic metabolic acidosis, including diabetic ketoacidosis.
• Pregnant or breastfeeding women should use this medication only if clearly needed and after discussing the potential risks and benefits with their healthcare provider.