Teneligliptin 20 mg and Metformin Hydrochloride 1000 mg Extended Release Tablets

Uses

This medication is primarily used in the treatment of type 2 diabetes mellitus in adults, particularly in cases where diet and exercise alone have not been sufficient to control blood sugar levels. It is effective in improving glycemic control by increasing insulin release and decreasing sugar production in the liver.

Benefits

The combination of Teneligliptin and Metformin Hydrochloride offers several benefits, including:

• Improved blood sugar control throughout the day.
• Reduced risk of hypoglycemia (low blood sugar) compared to other therapies.
• Potential weight management advantages due to the effects of Metformin.
• Convenient once-daily dosing that may improve patient adherence to the medication.

Side Effects

While Teneligliptin and Metformin Hydrochloride are generally well-tolerated, some individuals may experience side effects such as:

• Nausea or vomiting
• Diarrhea
• Abdominal pain
• Loss of appetite
• Vitamin B12 deficiency
• Rarely, a condition known as lactic acidosis, which is more common in patients with kidney problems

How to Use

These tablets should be taken once daily with meals to reduce gastrointestinal side effects. It is important to swallow the tablet whole and not to crush or chew it. The dose and duration of the treatment should be as prescribed by a healthcare professional.

How It Works

Teneligliptin works by inhibiting the enzyme DPP-4, which increases the levels of incretin hormones, enhancing insulin secretion in response to meals and decreasing glucagon release. Metformin decreases glucose production in the liver, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Together, these actions help control blood glucose levels.

Storage

Store the tablets in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets.

Caution and Warning

• Not suitable for patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.
• Should be used with caution in patients with renal or hepatic impairment.
• Regular monitoring of blood sugar levels, kidney function, and vitamin B12 levels is recommended during treatment.
• Inform your healthcare provider of all medications you are taking, as there may be potential interactions.
• Pregnant or breastfeeding women should use this medication only if clearly needed and after consulting a healthcare provider.