Aceclofenac (Zerodol TH OD) is a nonsteroidal agent with marked anti-inflammatory and analgesic properties. It has higher anti-inflammatory action than conventional NSAIDs and is a cytokine inhibitor. The mode of action of Aceclofenac (Zerodol TH OD) is largely based on the inhibition of prostaglandin synthesis. Aceclofenac (Zerodol TH OD) is a potent inhibitor of the enzyme cyclooxygenase, inflammatory cytokines interleukin IL1, tumor necrosis factor and prostaglandins E2. Cyclooxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation.
Prescription: Yes
Warnings: If you are allergic to Zerodol Th Od 8mg Capsule 5's or any other medicines, please tell your doctor. Zerodol Th Od 8mg Capsule 5's is not recommended for children below 18 years of age. Avoid taking Zerodol Th Od 8mg Capsule 5's if you are pregnant as it may cause harm to the foetus. Zerodol Th Od 8mg Capsule 5's is excreted in breast milk. Therefore, Zerodol Th Od 8mg Capsule 5's is contraindicated in breastfeeding women as it may cause adverse effects in the baby. Do not consume alcohol with Zerodol Th Od 8mg Capsule 5's as it may increase the risk of severe adverse effects. If you have asthma, diabetes, high blood pressure, stomach ulcer, high cholesterol, chickenpox, porphyria (rare inherited disorder), systemic lupus erythematosus (an autoimmune disease), ulcerative colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss), galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), fits, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), bleeding or blood clotting disorders, kidney, liver or heart diseases, inform your doctor before taking Zerodol Th Od 8mg Capsule 5's.
Medicine Interaction: Zerodol Th Od 8mg Capsule 5's may have interaction with medicines used to lower high blood pressure (lisinopril, enalapril, candesartan, losartan, clonidine, moxonidine, hydralazine, methyldopa, propranolol), antibiotics (ciprofloxacin, moxifloxacin, ofloxacin, levofloxacin), water pills (furosemide, amiloride), blood thinners (heparin, warfarin, clopidogrel), anticancer drug (methotrexate), HIV drug (zidovudine), antidiabetic drugs (gliclazide, tolbutamide, glibenclamide), pain killers (ibuprofen, naproxen, aspirin, celecoxib, etoricoxib), steroids (hydrocortisone, prednisolone), medicines used for abortion (mifepristone), immunosuppressants (ciclosporin, tacrolimus), antimanic drug (lithium), heart-related medicines (digoxin), and antidepressants (fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram).
Drug Schedule: Schedule H Prescription Drug
Side Effects: Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Rare
Body spasm, with head and heels bent backward and body bowed forward
convulsions (seizures)
depression
shakiness or tremors
skin rash
sore throat or fever
unusual tiredness
vomiting (severe or continuing)
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Drowsiness
Less common
Blurred vision
diarrhea
dizziness
headache
muscle cramps
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
How to Store it: Store in a cool dry Place below 30C, Protected From Light and Moisture.
Over Dose: When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
Precautions: Before using Zerodol TH OD Capsule, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
Avoid driving and operate dangerous machinery
Gastro-intestinal disorders
History of gastroulceration
Limit alcoholic beverages
Patients recovering after a surgery
Severe cardiac impairment
Severe hepatic impairment
Severe renal impairment
Usage of diuretics
Missed Dose: In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
