Chlorthalidone (Olkem TRIO) is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Chlorthalidone (Olkem TRIO) is also used to treat fluid retention (edema) that is caused by congestive heart failure, severe liver disease (cirrhosis), kidney disease, or treatment with a hormone or steroid medicine.
Chlorthalidone (Olkem TRIO) is a diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps to lower blood pressure.
Chlorthalidone (Olkem TRIO) is available only with your doctor’s prescription.
Prescription: Yes
Warnings: Olkem Trio 6.25 Tablet 10's should not be given to the people allergic to Olkem Trio 6.25 Tablet 10's, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Olkem Trio 6.25 Tablet 10's can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Olkem Trio 6.25 Tablet 10's and breastfeeding. Grapefruit juice and St. John's wort plant should not be consumed when taking Olkem Trio 6.25 Tablet 10's as it is contraindicated. Olkem Trio 6.25 Tablet 10's contain hydrochlorothiazide which can cause hypokalaemia (low potassium), hyponatremia (low sodium) and hypomagnesemia (low magnesium). So regular monitoring of electrolytes is required while taking treatment with Olkem Trio 6.25 Tablet 10's. Do not take Olkem Trio 6.25 Tablet 10's if you have low or no urine output, allergic to other sulfonamide antibiotics, or taking aliskiren and have diabetes. Drinking alcohol while using Olkem Trio 6.25 Tablet 10's can cause you to have low blood pressure, so avoid intake of alcoholic beverages.
Medicine Interaction: Olkem Trio 6.25 Tablet 10's may interact with other high blood pressure-lowering pills (benazepril, metoprolol, ramipril, hydrochlorothiazide, simvastatin, diltiazem, aliskiren, verapamil, azilsartan, benazepril, lisinopril, amiloride), and can lower your blood pressure leading to severe condition. Besides this, medicine to treat erectile dysfunction (sildenafil), antibiotics (Clarinathromycin, erythromycin), anti TB drug (rifampicin), antifungal (itraconazole, ketoconazole), anti-HIV drugs (ritonavir), anti-epilepsy medicines (carbamazepine, phenytoin, phenobarbital, primidone), antibiotics (erythromycin), immune-suppressing drugs (cyclosporine, tacrolimus), and pain killers (ibuprofen, aspirin) should not be taken with Olkem Trio 6.25 Tablet 10's.
Side Effects: Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Abdominal or stomach pain
black, tarry stools
bleeding gums
blistering, peeling, or loosening of skin
bloating
blood in urine or stools
blurred vision
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain
chills
clay-colored stools
cold sweats
confusion
constipation
cough or hoarseness
coughing up blood
darkened urine
diarrhea
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
dry mouth
fast heartbeat
fatigue
fever
flushed, dry skin
fruit-like breath odor
general feeling of tiredness or weakness
headache
increased hunger
increased thirst
increased urination
indigestion
itching
joint pain, stiffness, or swelling
loss of appetite
lower back or side pain
Nausea
pain in joints or muscles
painful or difficult urination
pains in stomach, side, or abdomen, possibly radiating to the back
pinpoint red spots on skin
red irritated eyes
red skin lesions, often with a purple center
redness, soreness or itching skin
shortness of breath
skin rash
sore throat
sores, ulcers, or white spots on lips or in mouth
sores, welting, or blisters
sugar in the urine
sweating
swelling of feet or lower legs
swollen glands
tightness in chest
troubled breathing
unpleasant breath odor
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight loss
vomiting
vomiting of blood
weight loss
wheezing
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Cramping
decreased interest in sexual intercourse
difficulty having a bowel movement (stool)
feeling of constant movement of self or surroundings
hives
inability to have or keep an erection
increased sensitivity of skin to sunlight
loss in sexual ability, desire, drive, or performance
muscle spasm
redness or other discoloration of skin
restlessness
sensation of spinning
severe sunburn
weakness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
How to Store it: Store at a temperature Between 10 to 25 C. Protect from light.
Over Dose: Store at a temperature Between 10 to 25 C. Protect from light.
Precautions: Store at a temperature Between 10 to 25 C. Protect from light.
Missed Dose: Store at a temperature Between 10 to 25 C. Protect from light.
