How Are Pharmaceutical Tablets Manufactured at JoinHub Pharma?

By: February 24, 2022

The design and manufacturing of pharmaceutical tablets is a complex and multi-stage process. The formulation experts at JoinHub Pharma ensure that the correct amount of drug substance in the suitable form is delivered at the appropriate time, reasonable rate, and at the desired location with its chemical integrity protected to the extreme point.

Many drug substances do not possess the required properties, which give adequate flow from the hopper to the die cavity of tablet presses. Thus, they are subjected to pre-treatment either alone or in combination with suitable excipients to form free-flowing granules that lend themselves to tableting.

As a leading pharmaceutical tablet manufacturer, we at JoinHub Pharma manufacture tablets by wet granulation, dry granulation, or direct compression. These tablet manufacturing processes consist of a number of steps, including weighing, mixing, granulation, milling, drying, compaction, often coating, and packaging. The unit processes – milling, weighing, and mixing- are the same; subsequent steps differ regardless of which method is utilized.

Primary Goals of JoinHub Pharma’s Tablet Manufacturing Process

The primary goals include:

  • To formulate solid and hard tablets to resist mechanical shock encountered during production, packing, shipping, dispensing, and utilization.
  • To formulate tablets that are uniform in drug content and weight.
  • To formulate tablets that are bioavailable as per the indication requirements.
  • To formulate tablets that are physically and chemically stable over a long period.
  • To formulate tablets with an elegant product identity free from any tablet defects.

Categories of Pharma Tablet for Oral Use

  • Coated tablets
  • Uncoated tablets
  • Gastro-resistant tablets
  • Soluble tablets
  • Modified-release tablets
  • Dispersible tablets
  • Oral lyophilisates
  • Chewable tablets

How Tablets Are Manufactured at JoinHub Pharma

A tablet is a dosage form comprising a mixture of active substances and excipients in powder form in the pharmaceutical jargon.

The ingredients pass through a series of processes and compact into a solid dose. The excipients are:

  • Binders
  • Diluters
  • Glidants
  • Lubricants

The disintegrators are included to help break the pharma tablet into the digestive tract. Sometimes, flavors or sweeteners are added to make the tablet palatable. Polymer coating makes swallowing easy and controls an active ingredient’s release rate. It makes the tablet more environment-resistant.

Steps Involved in Pharmaceutical Tablet Manufacturing

All pharmaceutical tablets are manufactured in JoinHub Pharma’s WHO-GMP certified manufacturing units located in Ahmedabad.


Each ingredient in the tablet formula is weighed and precisely dispensed as per dose. This is considered as one of the critical steps in any type of formulation process and is done by our technical experts.


Formulation ingredients are equally separated in form; otherwise, reducing size needs to be carried out for better flow property and easy mixing.

Powder Blending

Powders are mixed utilizing a suitable blender to get a uniform and homogeneous powder mix. Further, the drug substance and excipients are blended in geometric dilution.


At this stage, tiny powder particles are gathered into layers and permanent aggregates to induce them into free-flowing forms.

Drying and Dry Screening

Screened wet granules are dried for a particular period in a tray dry or fluid bed dryer at a controlled temperature not more than 550C. Dried granules are screened via the appropriate mesh screen.

Tablet Compression

This step includes compression granules into flat or convex, oblong, round, or unique shaped, scored, or unscored tablets; engraved with a recognized symbol and/ or code number using a tablet press.


Granules and tablets are coated if there is a need to mask the unpleasant taste/odor of some drug substance or increase the aesthetic look of uncoated tablets and modify the release or control the release drug substance from tablets. This is accomplished by enclosing or covering the primary tablet or granules with coating solutions.

Packaging and Storing of Tablets

Before sending out tablets to the distributor, they are generally packaged using the latest packaging techniques and materials. The type of packaging material utilized is superior. We choose the material based on several factors, including:

  • Compatibility of the material with the formulation.
  • The degree of protection required.
  • Presentation, especially for those pharma products which may be the subject of impulse buying
  • Customer convenience in terms of weight, size, method of opening or reclosing, legibility of printing, etc.
  • Filling Method and
  • Cost

Types of Tablet Packaging:

Our top-notch pharma product packaging provides excellent environmental protection for each tablet unit, coupled with an aesthetically pleasing and productive appearance. At JoinHub Pharma, pharmaceutical tablets are typically packed using blister and strip packs and are kept in low humidity and save from extreme temperatures. Blister and strip packaging additionally offer some degree of tamper resistance to the dosage form.

Blister Packaging Tablets

This is a universal term for preformed plastic packaging for pharmaceuticals tablets. The major element of the blister pack is in the thermoformed plastic.

It has a fundamental tablet packaging that will envelop the product and keep it in place. The main components of the blister packs are the cavity and the lidding.

We will then cover it with secondary packaging for grouping all primary packages in one place. It further has an aluminum leading foil, paperboard backing, or plastic seal. You may also use a clamshell, a type of blister that folds onto itself.

We use the blister packages for unit packaging of doses.

Bottle Packaging of Tablets

We place the tablets in a bottle which is the primary package. After that, we cover the bottle with a lid which acts as the secondary package. This type of tablet packaging is used for very strong tablets that cannot break easily.

After packaging the tablets in either the blister package or bottle package, we place them in a tertiary package like boxes for bulk handling.

Let us proceed to the last section of this guide, covering the quality control tests.

For larger quantities delivered to the pharmacist, plastic or glass bottles, cartons, metal containers, or paperboard drums are used along with polyethylene liners, whenever required, to provide extra protection from moisture.

If cotton wool stuffing is used under these circumstances, we use external liners so that any moisture it contains does not gain access to the tablets. Tablets that are decomposed when exposed to moisture are packaged with a desiccant packet. Light-sensitive tablets are packaged in light-resistant containers. With just a couple of exemptions, tablets that are well stored will remain stable for many years.

Joinhub Pharma – A Leading Pharmaceutical Tablet Manufacturer

An ISO Certified Third-Party Pharmaceutical tablet manufacturing Company adheres to WHO, and GMP Guidelines have a Trusted name in providing Third-Party Manufacturing services for Tablets.

Being the Best Pharmaceutical Tablets Manufacturer in India, we offer to manufacture all Tablets segments such as analgesics, antibiotics, antiemetics, anti-infectives, anti-allergic, local anesthesia, anti-inflammatory, etc. We Manufacture tablets intending to be uniform in drug content and weight, chemically & really stable and free of defects. Also, it uses the latest packaging technologies Flexible selection of more modern and venerable science.

We always focus on manufacturing pharma tablets that are effective and hard to resist several movements without breaking yet become an easy solution in dissolution.

Looking for the best pharmaceutical tablet manufacturer and supplier in Latin America, South Africa, and the Middle East?

Want quality pharmaceuticals tablets drug/ medicines range? Look no further than JoinHub Pharma – The top pharmaceuticals tablets manufacturer in India that brings total quality controls, Schedule M units, best packaging technique, skilled brains, and quick distribution chains, all under one roof.

Reach out to our pharma experts today by just dropping an email at [email protected]

JoinHub Author
JoinHub Pharma
JoinHub Pharma is the swiftest and biggest developing pharmaceutical companies in India, with headquarters at Ahmedabad, Gujarat. We at JoinHub Pharma are committed to our employees and customers and all the more significantly, to the people who depend on our medicines.
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